The effect of ACE inhibitors on inflammation and clinical end-points in COVID-19 patients Relationship of ACE inhibitors to COVID-19 patients

Aim: COVID-19 infection has affected the whole world. It has been speculated that the virus might hold on to angiotensin-converting enzyme 2 (ACE 2) surfaces of type 2 alveolar cells. ACE inhibitors and angiotensin receptor antagonists (ARBs) are essential antihypertensive and cardiac failure drugs in the guidelines. In this study, we aimed to find the effect of these drugs on clinical, laboratory courses, and outcomes of COVID-19 patients. Material(s) and Method(s): We included 109 patients in this study. There were 43 patients in the ACE/ARB group and 66 patients in the non-ACE/ARB group. The mean age was 60 years in the ACE/ARB group and 52 years old in the non-ACE/ARB group. Basal symptoms, hemogram, CRP, D-dimer, LDH, Ferritin, AST, duration of hospitalization, percentage of intensive care unit (ICU) need, length of stay in ICU were compared between the groups. Result(s): The mean age in the ACE/ARB group was higher than in the other group and was statistically significant (p=.027). The initial symptoms were not different. There were no differences between the laboratory results of the groups. The ICU need was higher in the patients who do not use the drug than in the users (p<.020). Discussion(s): ACE/ARB usage in COVID-19 patients did not worsen the course of the disease. However, ACE/ARB users before COVID-19 pandemic were taken to ICU at a low rate.Copyright © 2022, Derman Medical Publishing. All rights reserved.

Development of a Full Face Mask during the COVID-19 Fpidemic Spread Period

Zoonotic retroviroses can cause widespread morbidity and mortality. Preventive vaccines are currently available for a limited number of viruses. Since an effective vaccine against COVIDI9 cannot he developed yet, personal protection equipment (PPE) is essential, especially for protecting the healthcare providers against such contaminations. Full fire protecting equipment has a vital role in PPE. During the April 2020 spreading period of the COVID-19 epidemic, filter adapters were required to create a snorkel based full fire musk as a PPE. This study aimed to report different production methods for filter adapters, features, advantages-disadvantages and combining the resulting mask's physical characteristics and cost analysis.

Development of a Full Face Mask during the COVID-19 Epidemic Spread Period

Zoonotic retroviruses can cause widespread morbidity and mortality. Preventive vaccines are currently available for a limited number of viruses. Since an effective vaccine against COVID19 cannot be developed yet, personal protection equipment (PPE) is essential, especially for protecting the healthcare providers against such contaminations. Full face protecting equipment has a vital role in PPE. During the April 2020 spreading period of the COVID-19 epidemic, filter adapters were required to create a snorkel based full face mask as a PPE. This study aimed to report different production methods for filter adapters, features, advantages-disadvantages and combining the resulting mask's physical characteristics and cost analysis. © 2020 IEEE.